TRANSMEMBRANE HELICES ARE AN OVER-PRESENTED AND EVOLUTIONARILY CONSERVED SOURCE OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I AND II EPITOPES

Transmembrane Helices Are an Over-Presented and Evolutionarily Conserved Source of Major Histocompatibility Complex Class I and II Epitopes

Cytolytic T cell responses are predicted to be biased towards membrane proteins.The peptide-binding grooves of most alleles of histocompatibility complex class I (MHC-I) are relatively hydrophobic, therefore peptide fragments derived from human transmembrane helices (TMHs) are predicted to be presented more often as would be expected based on their

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15-year Borrelia prevalence and species distribution monitoring in Ixodes ricinus/inopinatus populations in the city of Hanover, Germany

Lyme borreliosis, caused by Borrelia burgdorferi sensu lato (s.l.) spirochaetes, is the most common tick-borne disease (TBD) in the Northern Hemisphere.Rising incidences indicate that its epidemiology may be affected by global changes.Therefore, the current study aimed to assess changes in tick infection rates with Borrelia spp.over a 15-year monit

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Dry Ports-Seaports Sustainable Logistics Network Optimization: Considering the Environment Constraints and the Concession Cooperation Relationships

In China dry ports enter into a rapid nova medical products for sale in arizona development period now, however for many Chinese dry ports, the operation faces difficulties duo to inefficient logistics networks and cooperation relationship between dry ports and seaports.Focusing on the concession cooperation mechanism of seaports and dry ports, and

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